Prolene

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Prolene is a synthetic, non-absorbable polypropylene suture material widely used in surgery. It is known for its high tensile strength, minimal tissue reactivity, and long-term durability. Prolene is commonly used in various surgical procedures, including cardiovascular surgery, plastic surgery, and general surgery.

Properties[edit | edit source]

Prolene sutures are made from an isotactic crystalline stereoisomer of polypropylene, which gives them their unique properties. These sutures are characterized by their:

  • High tensile strength
  • Minimal tissue reactivity
  • Resistance to degradation by tissue enzymes
  • Smooth surface, which facilitates easy passage through tissues

Uses[edit | edit source]

Prolene is used in a variety of surgical applications due to its favorable properties. Some of the common uses include:

  • Cardiovascular surgery: Prolene is often used for anastomosis of blood vessels and for suturing prosthetic grafts.
  • Plastic surgery: It is used for skin closure and for suturing delicate tissues.
  • General surgery: Prolene is used for abdominal wall closure, hernia repair, and other soft tissue approximations.

Advantages[edit | edit source]

Prolene offers several advantages over other suture materials:

  • Long-term durability: Prolene sutures do not degrade over time, making them suitable for long-term tissue approximation.
  • Minimal tissue reaction: The inert nature of polypropylene minimizes the inflammatory response, reducing the risk of infection and promoting better healing.
  • High tensile strength: Prolene maintains its strength over time, providing reliable wound support.

Disadvantages[edit | edit source]

Despite its many advantages, Prolene has some limitations:

  • Handling characteristics: Prolene can be more difficult to handle compared to other suture materials due to its stiffness and memory.
  • Knot security: Achieving secure knots with Prolene can be challenging, requiring additional throws to ensure stability.

History[edit | edit source]

Prolene was developed in the mid-20th century as part of the search for better synthetic suture materials. Its introduction revolutionized surgical practice by providing a reliable, non-absorbable option for tissue approximation.

See also[edit | edit source]

References[edit | edit source]

External links[edit | edit source]


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Contributors: Prab R. Tumpati, MD