Propan-1-ol

From WikiMD's Food, Medicine & Wellness Encyclopedia

Propan-1-ol, also known as 1-propanol or n-propanol, is a primary alcohol with the chemical formula C3H8O. It is a colorless liquid commonly used as a solvent in the pharmaceutical industry, and also has applications in the creation of cosmetics, cleaning products, and as a precursor in the synthesis of other chemicals.

Properties[edit | edit source]

Propan-1-ol has a boiling point of 97.2°C and a melting point of -126.2°C. It is miscible with water, ethanol, ether, and most organic solvents, making it versatile for various industrial applications. Its solubility in water and its moderate volatility contribute to its use in household and industrial cleaning products.

Production[edit | edit source]

Propan-1-ol can be produced through the hydroformylation of ethylene to produce butyraldehyde, which is then hydrogenated to yield propan-1-ol. Another method involves the catalytic hydration of propylene. The production of propan-1-ol is significant in the chemical industry due to its use as a solvent and as a precursor to other compounds such as propyl acetate and propylamines.

Uses[edit | edit source]

Propan-1-ol is widely used as a solvent in the pharmaceutical industry for the production of various drugs and as a carrier for drug formulations. Its application extends to the cosmetics industry, where it is used in perfumes, lotions, and creams. In the industrial sector, propan-1-ol is utilized in the manufacture of cleaning agents, inks, and coatings due to its effectiveness in dissolving oils, resins, and cellulose.

Safety[edit | edit source]

Exposure to propan-1-ol can cause irritation to the eyes, skin, and respiratory system. Ingestion or inhalation of high concentrations can lead to central nervous system depression, characterized by dizziness, headache, and in severe cases, unconsciousness. Proper handling and ventilation are recommended when working with propan-1-ol to minimize exposure risks.

Environmental Impact[edit | edit source]

Propan-1-ol is considered to have a low potential for bioaccumulation and is readily biodegradable. However, its release into the environment should be controlled to prevent potential harm to aquatic life due to its toxicity at high concentrations.

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Contributors: Prab R. Tumpati, MD