Prostate specific antigen

It is a protein manufactured exclusively by the prostate gland.

Abbreviation

Prostate Specific Antigen is commonly abbreviated to PSA.

Function

PSA is produced for the ejaculate where it liquifies the semen and allows sperm cells to swim freely.

Elevated PSA

Elevated levels of PSA in blood serum are associated with benign prostatic hyperplasia and prostate cancer

Tumor marker assay (test)

Test of blood serum for prostate specific antigen released from cells in prostate tissue. Value may be elevated in benign prostatic hypertrophy. After radical prostatectomy or radiation therapy, rising levels of PSA indicate residual disease or recurrence.

Compounding factors

The test results may be affected by recent prostatic massage or palpation; PSA level should be assayed before digital rectal examination.

Normal values

PSA normal range is 0 - 4.0 ng/ml. However, normal range also varies depending on the patient's age.

Prostate specific antigen Resources
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