Triflupromazine

Triflupromazine is a phenothiazine derivative that is used as an antipsychotic and antiemetic medication. It is a member of the thioxanthene class of drugs and was developed in the 1950s.

Pharmacology

Triflupromazine works by blocking dopamine receptors in the brain, which helps to reduce psychotic symptoms such as hallucinations, delusions, and disorganized thinking. It also has antiemetic properties, meaning it can be used to treat nausea and vomiting.

Medical uses

Triflupromazine is used to treat a variety of conditions, including schizophrenia, bipolar disorder, and severe nausea and vomiting. It can also be used to calm and sedate patients before surgery or other medical procedures.

Side effects

Like all medications, triflupromazine can cause side effects. These may include drowsiness, dizziness, dry mouth, constipation, and blurred vision. In rare cases, it can cause serious side effects such as tardive dyskinesia, a condition characterized by involuntary movements of the face and body.

History

Triflupromazine was first synthesized in the 1950s as part of a class of drugs known as phenothiazines. These drugs were initially developed as antihistamines, but were later found to have antipsychotic properties.

See also

• Phenothiazine
• Antipsychotic
• Antiemetic