Puumala orthohantavirus

Puumala orthohantavirus (PUUV) is a species of Hantavirus that is primarily carried by the bank vole (Myodes glareolus). It is named after the Puumala region in Finland where the virus was first isolated. PUUV is the cause of a mild form of Hantavirus hemorrhagic fever with renal syndrome (HFRS), also known as Nephropathia epidemica.

Transmission

PUUV is primarily transmitted to humans through inhalation of aerosolized virus particles from the feces, urine, or saliva of infected bank voles. Direct contact with infected rodents or their droppings, or bites from infected rodents can also result in transmission. Human-to-human transmission is extremely rare.

Symptoms

The symptoms of PUUV infection include fever, headache, backache, abdominal pain, and renal dysfunction. In severe cases, it can lead to hemorrhagic fever and renal failure. The incubation period is typically 2-4 weeks.

Diagnosis

Diagnosis of PUUV infection is based on clinical symptoms and confirmed by laboratory tests. These tests typically involve detection of specific antibodies in the patient's blood.

Treatment

There is no specific treatment for PUUV infection. Management of the disease involves supportive care, including rehydration and pain management. In severe cases, hospitalization may be required.

Prevention

Prevention of PUUV infection involves avoiding contact with rodents and their droppings, and maintaining good hygiene in areas where rodents are present.

See also

• Hantavirus
• Hantavirus hemorrhagic fever with renal syndrome
• Nephropathia epidemica

Puumala orthohantavirus Resources
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