Pyloric orifice

Pyloric Orifice is a part of the human digestive system, specifically located in the stomach. It is the opening from the stomach into the duodenum, the first part of the small intestine. The term "pyloric" is derived from the Greek word "pyloreus" meaning "gatekeeper", which is an apt description for its function in the digestive process.

Anatomy

The pyloric orifice is situated at the end of the pyloric canal, which is the final part of the stomach. It is surrounded by a strong circular muscle known as the pyloric sphincter. This muscle controls the passage of partially digested food, known as chyme, from the stomach into the duodenum.

Function

The primary function of the pyloric orifice is to regulate the flow of chyme into the small intestine. The pyloric sphincter contracts and relaxes in a process known as gastric emptying, allowing small amounts of chyme to pass through the pyloric orifice at a time. This ensures that the small intestine is not overloaded with food, allowing for efficient digestion and absorption of nutrients.

Clinical Significance

The pyloric orifice and the pyloric sphincter play a crucial role in the digestive process, and any abnormalities can lead to digestive disorders. One such condition is pyloric stenosis, which is a narrowing of the pyloric orifice that can cause severe vomiting in infants. Another condition is peptic ulcer disease, which can cause the pyloric sphincter to malfunction, leading to acid reflux and other symptoms.

See Also

• Human digestive system
• Stomach
• Duodenum
• Pyloric stenosis
• Peptic ulcer disease