Peptic ulcer

From WikiMD's Wellness Encyclopedia

Ulcer of an area of the gastrointestinal tract


Peptic ulcer disease
Synonyms Peptic ulcer, stomach ulcer, gastric ulcer, duodenal ulcer
Pronounce N/A
Field Gastroenterology
General surgery
Symptoms Heartburn, Upper abdominal pain, nausea, belching, vomiting, blood in the stool, weight loss, Weight gain, bloating, loss of appetite[1] yellowing of the skin and whites of the eyes difficulty swallowing
Complications Bleeding, perforation, ulcer perforation, blockage of the stomach[2]
Onset
Duration
Types N/A
Causes Helicobacter pylori, non-steroidal anti-inflammatory drugs, tobacco smoking, Crohn disease[1][3]
Risks
Diagnosis Based on symptoms, confirmed by endoscopy or barium swallow[1]
Differential diagnosis Stomach cancer, coronary heart disease, inflammation of the stomach lining, gallbladder inflammation[1]
Prevention
Treatment Stopping smoking, stopping NSAIDs, stopping alcohol, medications[1]
Medication Proton pump inhibitor, H2 blocker, antibiotics[1][4]
Prognosis
Frequency 87.4 million (2015)[5]
Deaths 267,500 (2015)[6]


Peptic ulcer is an erosion in the lining of the esophagus, stomach, or duodenum, usually caused in part by the corrosive action of gastric acid.

Risk factors[edit | edit source]

People who take NSAIDs such as aspirin and ibuprofen long-term or are infected with the bacteria H. pylori are most likely to develop peptic ulcers.

Depiction of a patient suffering from peptic ulcers
Depiction of a patient suffering from peptic ulcers

Symptoms[edit | edit source]

A dull or burning pain in the stomach is the most common symptom of peptic ulcers (stomach ulcers).

Causes[edit | edit source]

Causes include long-term use of NSAIDs, an infection with H.pylori, or both. Rarely, tumors cause peptic ulcers.

Diagnosis[edit | edit source]

Peptic ulcers have different symptoms and causes, but only endoscopy or an Barium X-ray that can determine if you have one.

Treatment[edit | edit source]

Your doctor will decide the best treatment based on the cause of your peptic ulcer (stomach ulcer). Most ulcers heal from treatment with Proton Pump Inhibitors (PPIs). If an ulcer is caused by NSAID’s, your doctor may tell you to stop taking them.

Diet[edit | edit source]

Different foods do not cause or prevent peptic ulcers (stomach ulcers), but drinking alcohol does make ulcers worse.


Classification
External resources


Health science - Medicine - Gastroenterology - edit
Diseases of the esophagus - stomach
Halitosis | Nausea | Vomiting | GERD | Achalasia | Esophageal cancer | Esophageal varices | Peptic ulcer | Abdominal pain | Stomach cancer | Functional dyspepsia | Gastroparesis
Diseases of the liver - pancreas - gallbladder - biliary tree
Hepatitis | Cirrhosis | NASH | PBC | PSC | Budd-Chiari | Hepatocellular carcinoma | Acute pancreatitis | Chronic pancreatitis | Pancreatic cancer | Gallstones | Cholecystitis
Diseases of the small intestine
Peptic ulcer | Intussusception | Malabsorption (e.g. Coeliac, lactose intolerance, fructose malabsorptionWhipple's) | Lymphoma
Diseases of the colon
Diarrhea | Appendicitis | Diverticulitis | Diverticulosis | IBD (Crohn'sUlcerative colitis) | IBS | Constipation | Colorectal cancer | Hirschsprung's | Pseudomembranous colitis

Peptic ulcer Resources
Wikipedia
  1. 1.0 1.1 1.2 1.3 1.4 1.5 Cite error: Invalid <ref> tag; no text was provided for refs named Na2011
  2. Cite error: Invalid <ref> tag; no text was provided for refs named Mil2011
  3. Cite error: Invalid <ref> tag; no text was provided for refs named St2002
  4. Cite error: Invalid <ref> tag; no text was provided for refs named Wang2011
  5. Cite error: Invalid <ref> tag; no text was provided for refs named GBD2015Pre
  6. Cite error: Invalid <ref> tag; no text was provided for refs named GBD2015De
WikiMD
Navigation: Wellness - Encyclopedia - Health topics - Disease Index‏‎ - Drugs - World Directory - Gray's Anatomy - Keto diet - Recipes

Search WikiMD

Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD

WikiMD's Wellness Encyclopedia

Let Food Be Thy Medicine
Medicine Thy Food - Hippocrates

Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.

Contributors: Prab R. Tumpati, MD