Pyridoxine/doxylamine

Pyridoxine/doxylamine is a combination of two medications, pyridoxine and doxylamine, used primarily in the management of nausea and vomiting associated with pregnancy. This medication is considered a first-line treatment for this condition, also known as morning sickness.

Composition

The medication is composed of 10 mg of pyridoxine (vitamin B6) and 10 mg of doxylamine (an antihistamine). These two active ingredients work together to alleviate the symptoms of morning sickness.

Mechanism of Action

While the exact mechanism of action is not fully understood, it is believed that pyridoxine/doxylamine works by blocking the effects of chemicals in the body that trigger nausea and vomiting. Pyridoxine is thought to work on the nausea center in the brain, while doxylamine may work by blocking histamine, a substance in the body that can cause vomiting.

Usage

Pyridoxine/doxylamine is typically taken at bedtime on an empty stomach. If symptoms persist, additional doses can be taken in the morning and mid-afternoon. It is important to follow the prescribing doctor's instructions when taking this medication.

Side Effects

Common side effects of pyridoxine/doxylamine include drowsiness, dizziness, and dry mouth. If these effects persist or worsen, the patient should contact their doctor or pharmacist promptly.

Precautions

Before taking pyridoxine/doxylamine, patients should inform their doctor or pharmacist if they are allergic to either of the ingredients, or if they have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems.

Interactions

Drug interactions may change how medications work or increase the risk for serious side effects. It is important to keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist.

See Also

• Vitamin B6
• Antihistamines
• Morning sickness
• Drug interactions