RB-101
RB-101 is a drug that acts as an enzyme inhibitor, specifically inhibiting the enzyme enkephalinase, which breaks down enkephalins, a type of endogenous opioid in the body. RB-101 is a prodrug which is converted into the active compound, RB-120, in the body. This drug has been researched for its potential use in the treatment of pain, depression, and addiction.
Mechanism of action[edit | edit source]
RB-101 works by inhibiting the enzyme enkephalinase, which is responsible for the degradation of enkephalins. Enkephalins are endogenous opioids, meaning they are opioids that are naturally produced by the body. By inhibiting the breakdown of these opioids, RB-101 increases their concentration in the body, leading to increased opioid activity.
Potential therapeutic uses[edit | edit source]
RB-101 has been researched for its potential use in several therapeutic areas. These include the treatment of pain, depression, and addiction.
Pain[edit | edit source]
RB-101 has been shown to have analgesic effects in animal models of pain. This is likely due to its ability to increase the concentration of enkephalins in the body, which have analgesic properties.
Depression[edit | edit source]
Research has suggested that RB-101 may have antidepressant effects. This is thought to be due to its ability to increase the concentration of enkephalins, which have been shown to have mood-enhancing properties.
Addiction[edit | edit source]
RB-101 has been researched for its potential use in the treatment of addiction. This is due to its ability to increase the concentration of enkephalins, which have been shown to reduce the rewarding effects of addictive substances.
See also[edit | edit source]
| RB-101 Resources | |
|---|---|
|
 |
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
