Beta-Hydroxy beta-methylbutyric acid
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β-Hydroxy β-methylbutyric acid (HMB)[edit | edit source]
Overview[edit | edit source]
β-Hydroxy β-methylbutyric acid (HMB), also known as its conjugate base, β-hydroxy β-methylbutyrate, is a naturally produced substance in humans. It plays a significant role in muscle health and is used both as a dietary supplement and as an ingredient in certain medical foods.
Role in the Body[edit | edit source]
HMB is involved in the synthesis of muscle tissue and has been shown to reduce muscle breakdown. It is a metabolite of the essential amino acid Leucine, which is known for its role in protein synthesis and muscle repair.
Medical and Dietary Uses[edit | edit source]
HMB supplements are used to promote wound healing and provide nutritional support for people with muscle wasting due to conditions like Cancer or HIV/AIDS. It is particularly beneficial for preserving muscle mass in individuals who are immobilized or undergoing periods of muscle disuse.
Benefits in Exercise and Recovery[edit | edit source]
In healthy adults, supplementation with HMB has been shown to:
- Increase exercise-induced gains in muscle size, muscle strength, and lean body mass.
- Reduce skeletal muscle damage from exercise.
- Improve aerobic exercise performance.
- Expedite recovery from exercise.
Research and Reviews[edit | edit source]
Medical reviews and meta-analyses indicate that HMB supplementation helps to preserve or increase lean body mass and muscle strength in individuals experiencing age-related muscle loss or other conditions leading to muscle atrophy.
Safety and Dosage[edit | edit source]
The safety profile of HMB supplementation is generally considered good, but as with any supplement, it should be used under the guidance of a healthcare professional.
References[edit | edit source]
Resources[edit source]
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