RTI 3021–012

RTI 3021–012‏‎ is a synthetic compound that belongs to the Phenyltropane family of psychoactive drugs. It is primarily used in scientific research, particularly in the field of neuroscience and pharmacology.

Chemistry

RTI 3021–012‏‎ is a phenyltropane derivative. Phenyltropanes are a family of drugs that have a tropane core structure. This core structure is a bicyclic structure, consisting of a six-membered ring fused to a five-membered nitrogen-containing ring. The phenyltropane structure is a common feature in a variety of naturally occurring alkaloids such as cocaine and synthetic drugs.

Pharmacology

In pharmacology, RTI 3021–012‏‎ is known for its high affinity for the dopamine transporter (DAT). The dopamine transporter is a membrane-spanning protein that pumps the neurotransmitter dopamine out of the synapse back into cytosol, from which other transporters sequester the neurotransmitter into vesicles for storage and later release. Drugs that are potent DAT ligands have the potential for use in treating diseases such as Parkinson's disease and depression.

Research Use

RTI 3021–012‏‎ is primarily used in scientific research. It is often used as a ligand in the study of the dopamine transporter. By binding to the transporter, it can help scientists visualize the transporter in brain tissue. This can provide valuable information about the function and distribution of the transporter in the brain, which can be useful in understanding diseases that involve the dopamine system.

See Also

• Phenyltropane
• Dopamine transporter
• Psychoactive drug