Radiolabeled
Radiolabeled refers to the process of attaching a radioactive isotope to a molecule, often for the purpose of tracking or imaging in medical and biological research. This technique is commonly used in nuclear medicine, biochemistry, and molecular biology.
Overview[edit | edit source]
Radiolabeling involves the use of radioactive isotopes, which are atoms with an unstable nucleus. These isotopes emit radiation as they decay, which can be detected and measured. By attaching these isotopes to molecules of interest, researchers can track the movement and interactions of these molecules within a system.
Process[edit | edit source]
The process of radiolabeling typically involves the use of a radioactive isotope, such as tritium or carbon-14, and a molecule of interest. The isotope is attached to the molecule using a chemical reaction, often facilitated by an enzyme or other catalyst. Once the isotope is attached, the molecule can be introduced into a system and tracked using a radiation detector.
Applications[edit | edit source]
Radiolabeling has a wide range of applications in medical and biological research. In nuclear medicine, it is used to create radiopharmaceuticals, which are drugs that contain a radioactive isotope. These drugs can be used to image the body, diagnose disease, or deliver targeted radiation therapy. In biochemistry and molecular biology, radiolabeling is used to track the movement and interactions of molecules within cells and tissues.
Risks[edit | edit source]
While radiolabeling is a powerful tool for research, it also carries some risks. The radioactive isotopes used in this process emit radiation, which can be harmful to living tissue. Therefore, it is important to handle these isotopes with care and to minimize exposure.
See also[edit | edit source]
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Contributors: Prab R. Tumpati, MD