Dapiprazole

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Dapiprazole is a type of pharmaceutical drug that is primarily used in the field of ophthalmology. It is an alpha blocker, specifically an alpha-1 blocker, which means it works by blocking certain receptors in the body to achieve its effects.

Etymology[edit | edit source]

The name "Dapiprazole" is derived from the chemical name of the drug, which is 7-[2-[4-(2-methylphenyl)-1-piperazinyl]ethyl]-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione.

Uses[edit | edit source]

Dapiprazole is used to reverse the effects of phenylephrine and other mydriatic agents, which are drugs that dilate the pupil of the eye. This is useful in ophthalmology, as it allows doctors to return a patient's pupils to their normal size after they have been dilated for an examination.

Mechanism of Action[edit | edit source]

As an alpha-1 blocker, Dapiprazole works by blocking the alpha-1 adrenergic receptors in the iris of the eye. This prevents the action of substances like phenylephrine, which act on these receptors to dilate the pupil.

Side Effects[edit | edit source]

Like all drugs, Dapiprazole can have side effects. These can include conjunctivitis, blepharitis, and discomfort in the eye. In rare cases, it can cause more serious side effects like hypotension (low blood pressure) and tachycardia (fast heart rate).

Related Terms[edit | edit source]

Dapiprazole Resources
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Contributors: Prab R. Tumpati, MD