Rheumatoid neutrophilic dermatitis
Rheumatoid Neutrophilic Dermatitis
Rheumatoid Neutrophilic Dermatitis (RND) is a rare skin condition associated with Rheumatoid Arthritis. It is characterized by skin lesions that typically appear on the extremities. The condition is often misdiagnosed due to its rarity and the non-specific nature of the skin lesions.
Etiology[edit | edit source]
RND is most commonly associated with severe, active Rheumatoid Arthritis. However, it can also occur in patients with other systemic diseases such as Systemic Lupus Erythematosus and Sjögren's Syndrome. The exact cause of RND is unknown, but it is thought to be related to the immune response in these systemic diseases.
Clinical Presentation[edit | edit source]
Patients with RND typically present with skin lesions that are red, raised, and often painful. The lesions can appear anywhere on the body, but are most commonly found on the extremities. Other symptoms may include fever, joint pain, and fatigue.
Diagnosis[edit | edit source]
Diagnosis of RND is often challenging due to its rarity and the non-specific nature of the skin lesions. It is typically diagnosed through a combination of clinical presentation, patient history, and skin biopsy. The biopsy will show a dense infiltrate of neutrophils in the dermis, which is characteristic of RND.
Treatment[edit | edit source]
Treatment of RND is primarily focused on managing the underlying systemic disease. This may include medications to reduce inflammation and suppress the immune system. Topical or systemic corticosteroids may also be used to manage the skin lesions.
Prognosis[edit | edit source]
The prognosis for RND is generally good, with most patients experiencing a resolution of skin lesions with appropriate treatment. However, the underlying systemic disease may continue to cause symptoms and require ongoing management.
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
WikiMD's Wellness Encyclopedia |
Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
WikiMD is not a substitute for professional medical advice. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD