Netarsudil/latanoprost
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Netarsudil/Latanoprost is a combination drug used for the treatment of glaucoma and ocular hypertension. It is a combination of two active ingredients, Netarsudil and Latanoprost, which work together to reduce intraocular pressure.
Etymology[edit | edit source]
The name "Netarsudil" is derived from the chemical name "N-ethyltartrate-sudil". "Latanoprost" is derived from the Latin words "lata" meaning wide and "prost" meaning first, referring to its use as a first-line treatment for wide-angle glaucoma.
Pharmacology[edit | edit source]
Netarsudil is a Rho kinase inhibitor and norepinephrine transporter inhibitor. It works by increasing the outflow of aqueous humor, the fluid in the eye, thereby reducing intraocular pressure. Latanoprost is a prostaglandin analogue. It works by increasing the outflow of aqueous humor through the uveoscleral pathway, an alternative pathway for fluid to exit the eye.
Indications[edit | edit source]
Netarsudil/Latanoprost is indicated for the reduction of elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension.
Side Effects[edit | edit source]
The most common side effects of Netarsudil/Latanoprost include conjunctival hyperemia, corneal verticillata, instillation site pain, and conjunctival hemorrhage.
Related Terms[edit | edit source]
- Glaucoma
- Ocular hypertension
- Intraocular pressure
- Aqueous humor
- Rho kinase inhibitor
- Norepinephrine transporter inhibitor
- Prostaglandin analogue
- Uveoscleral pathway
- Conjunctival hyperemia
- Corneal verticillata
- Instillation site pain
- Conjunctival hemorrhage
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