Rosiglitazone/metformin

Rosiglitazone/metformin is a prescription medication used in the treatment of type 2 diabetes. It is a combination of two drugs, rosiglitazone and metformin, which work together to improve blood sugar control.

Overview

Rosiglitazone/metformin is marketed under the brand name Avandamet by GlaxoSmithKline. It is part of a class of medications known as thiazolidinediones and biguanides. Rosiglitazone works by increasing the body's sensitivity to insulin, a hormone that regulates the absorption of sugar into cells. Metformin, on the other hand, decreases the amount of sugar produced by the liver and absorbed by the intestines.

Medical uses

Rosiglitazone/metformin is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes. It is used when diet and exercise alone does not control blood sugar.

Side effects

Common side effects of rosiglitazone/metformin include headache, muscle pain, and nausea. Serious side effects may include lactic acidosis, heart failure, and liver problems.

Contraindications

Rosiglitazone/metformin is contraindicated in patients with renal disease, metabolic acidosis, and heart failure. It should not be used in patients with type 1 diabetes or for the treatment of diabetic ketoacidosis.

See also

• List of drugs used for diabetes
• Biguanide
• Thiazolidinedione

Rosiglitazone/metformin Resources
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