Rosiglitazone/metformin
Rosiglitazone/metformin is a prescription medication used in the treatment of type 2 diabetes. It is a combination of two drugs, rosiglitazone and metformin, which work together to improve blood sugar control.
Overview[edit | edit source]
Rosiglitazone/metformin is marketed under the brand name Avandamet by GlaxoSmithKline. It is part of a class of medications known as thiazolidinediones and biguanides. Rosiglitazone works by increasing the body's sensitivity to insulin, a hormone that regulates the absorption of sugar into cells. Metformin, on the other hand, decreases the amount of sugar produced by the liver and absorbed by the intestines.
Medical uses[edit | edit source]
Rosiglitazone/metformin is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes. It is used when diet and exercise alone does not control blood sugar.
Side effects[edit | edit source]
Common side effects of rosiglitazone/metformin include headache, muscle pain, and nausea. Serious side effects may include lactic acidosis, heart failure, and liver problems.
Contraindications[edit | edit source]
Rosiglitazone/metformin is contraindicated in patients with renal disease, metabolic acidosis, and heart failure. It should not be used in patients with type 1 diabetes or for the treatment of diabetic ketoacidosis.
See also[edit | edit source]
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Contributors: Prab R. Tumpati, MD
