S-14,506

S-14,506

0S-14,506 is a pharmacological compound that belongs to the class of serotonin receptor agonists. It is specifically a 5-HT1A receptor agonist, which means it binds to and activates this specific subtype of serotonin receptors in the brain.

Pharmacology

S-14,506 is a potent and selective 5-HT1A receptor agonist. The 5-HT1A receptor is one of the several different types of receptors for serotonin, a key neurotransmitter in the brain. Activation of 5-HT1A receptors has been linked to a variety of therapeutic effects, including anxiolytic and antidepressant effects.

Therapeutic Use

While S-14,506 itself is not used clinically, it has been extensively studied in preclinical research as a tool to understand the role of 5-HT1A receptors in various neuropsychiatric disorders. These include depression, anxiety disorders, and schizophrenia.

Chemistry

S-14,506 is a synthetic compound. Its chemical structure is distinct from that of serotonin, but it has been designed to bind to the same receptors in the brain.

Research

Research on S-14,506 has contributed to our understanding of the role of 5-HT1A receptors in the brain. For example, studies using this compound have shown that activation of these receptors can have potent antidepressant and anxiolytic effects. This has led to the development of several clinically used drugs that also target these receptors.

See Also

• 5-HT1A receptor
• Serotonin receptor agonists
• Neurotransmitter
• Neuropsychiatric disorders