SAMD4A
SAMD4A (Sterile Alpha Motif Domain Containing 4A) is a protein that in humans is encoded by the SAMD4A gene. This protein is part of the SAMD protein family, which is characterized by the presence of a Sterile Alpha Motif (SAM). SAM domains are known to be involved in diverse biological processes, which include RNA binding and signal transduction.
Function[edit | edit source]
The SAMD4A protein is believed to play a crucial role in the regulation of gene expression. It is thought to act as a translational repressor, which means it can inhibit the process of translation, the process by which proteins are synthesized in cells. However, the exact mechanisms by which SAMD4A exerts its function are still not fully understood and are the subject of ongoing research.
Clinical significance[edit | edit source]
Mutations in the SAMD4A gene have been associated with a variety of human diseases. For example, some studies have suggested a link between SAMD4A and cancer, with alterations in the gene potentially contributing to the development and progression of the disease. However, more research is needed to fully understand the role of SAMD4A in human health and disease.
See also[edit | edit source]
References[edit | edit source]
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Contributors: Prab R. Tumpati, MD