SB-705498

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SB-705498 is a chemical compound that is used in pharmacology as a potential treatment for various conditions. It is a potent and selective agonist for the TRPV1 receptor, which is involved in the transmission and modulation of pain, as well as the regulation of body temperature.

Chemistry[edit | edit source]

SB-705498 is a synthetic compound. It is classified as a benzazepine, which is a type of heterocyclic compound. Benzazepines are seven-membered rings that contain one nitrogen atom and two double bonds. They are known for their wide range of biological activities.

Pharmacology[edit | edit source]

SB-705498 acts as an agonist at the TRPV1 receptor. The TRPV1 receptor is a member of the TRP family of ion channels, which are involved in a wide range of sensory processes, including pain, temperature, taste, and pressure. By activating this receptor, SB-705498 can potentially modulate these sensory processes.

Clinical significance[edit | edit source]

Research into the therapeutic potential of SB-705498 is ongoing. It has been investigated for use in conditions such as chronic cough, neuropathic pain, and migraine. However, as of now, it is not approved for use in any country.

See also[edit | edit source]

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Contributors: Prab R. Tumpati, MD