SCH-23390
SCH-23390 is a drug that acts as a potent and selective antagonist for the D1-like dopamine receptor. It was the first selective antagonist for the D1 receptor to be discovered. SCH-23390 is often used in scientific research to study the effects of dopamine on the brain.
Pharmacology[edit | edit source]
SCH-23390 acts as a potent and selective antagonist for the D1-like dopamine receptor. It has a high affinity for the D1 receptor and a much lower affinity for the D2 receptor. SCH-23390 is also a weak antagonist for the 5-HT2C receptor and the α1B-adrenergic receptor.
Uses[edit | edit source]
SCH-23390 is primarily used in scientific research to study the effects of dopamine on the brain. It is often used in animal studies to block the effects of drugs that increase dopamine activity, such as cocaine and amphetamine. It has also been used in studies investigating the role of dopamine in reward, motor coordination, and memory.
Side Effects[edit | edit source]
As a research chemical, SCH-23390 is not intended for human consumption, so information on its side effects is limited. However, in animal studies, it has been shown to cause hyperactivity, agitation, and tremors when administered at high doses.
See Also[edit | edit source]
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