Sampaolesi line

Sampaolesi line is a term used in ophthalmology to refer to a pigmented line seen in the cornea of the eye. It is named after the Argentine ophthalmologist, Juan Sampaolesi, who first described it. The Sampaolesi line is often associated with glaucoma, particularly pigment dispersion syndrome and pseudoexfoliation syndrome.

Overview

The Sampaolesi line is a pigmented line visible on the corneal endothelium, typically seen in patients with pigment dispersion syndrome or pseudoexfoliation syndrome. These conditions are both types of glaucoma, a group of eye conditions that damage the optic nerve and can lead to vision loss or blindness.

Clinical Significance

The presence of a Sampaolesi line can be a significant finding in the diagnosis and management of glaucoma. It is often one of the first signs of pigment dispersion syndrome or pseudoexfoliation syndrome. The line is caused by the accumulation of pigment granules on the corneal endothelium, which can obstruct the drainage of aqueous humor from the eye, leading to increased intraocular pressure and potential damage to the optic nerve.

Diagnosis

The Sampaolesi line can be observed during a routine eye examination using a slit lamp. This device allows the ophthalmologist to examine the structures at the front of the eye under high magnification. The line appears as a band of increased pigmentation along the corneal endothelium, typically more prominent in the inferior part of the cornea.

Treatment

The treatment for conditions associated with a Sampaolesi line typically involves managing the underlying glaucoma. This can include medications to reduce intraocular pressure, laser therapy, or surgery. Regular monitoring of intraocular pressure and visual field testing are also important components of management.

See Also

• Glaucoma
• Pigment dispersion syndrome
• Pseudoexfoliation syndrome
• Juan Sampaolesi
• Slit lamp

References

Sampaolesi line Resources
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