Scientific Advisory Group for Origins of Novel Pathogens

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Advisory group for investigating pathogen origins


Scientific Advisory Group for Origins of Novel Pathogens[edit | edit source]

The Scientific Advisory Group for the Origins of Novel Pathogens (SAGO) is an international body established by the World Health Organization (WHO) to provide guidance and advice on the origins of emerging and re-emerging pathogens of epidemic and pandemic potential. The group plays a crucial role in understanding how novel pathogens, such as viruses, emerge and spread, which is essential for preventing future outbreaks and pandemics.

The novel coronavirus SARS-CoV-2, which caused the COVID-19 pandemic, is an example of a pathogen whose origins are studied by SAGO.

Purpose and Objectives[edit | edit source]

The primary purpose of SAGO is to advise the WHO on technical and scientific matters related to the origins of novel pathogens. This includes:

  • Evaluating current scientific knowledge on pathogen origins.
  • Identifying gaps in knowledge and research needs.
  • Providing recommendations for studies and investigations.
  • Advising on the development of frameworks and guidelines for pathogen origin studies.

SAGO aims to enhance global understanding of how pathogens like SARS-CoV-2 emerge, which is critical for developing strategies to prevent future pandemics.

Structure and Membership[edit | edit source]

SAGO is composed of experts from various fields, including virology, epidemiology, ecology, and public health. Members are selected based on their expertise and experience in relevant areas. The group is designed to be multidisciplinary, reflecting the complex nature of pathogen emergence.

The membership of SAGO is international, with experts from different regions to ensure a comprehensive global perspective. The group meets regularly to discuss ongoing research, review new data, and update their recommendations.

Activities and Initiatives[edit | edit source]

SAGO conducts a range of activities to fulfill its mandate, including:

  • Reviewing scientific literature and data on pathogen origins.
  • Organizing workshops and conferences to facilitate knowledge exchange.
  • Collaborating with other international organizations and research institutions.
  • Developing guidelines and protocols for conducting pathogen origin studies.

SAGO also plays a role in coordinating international efforts to investigate specific outbreaks and pandemics, providing scientific oversight and guidance.

Impact on Global Health[edit | edit source]

The work of SAGO is vital for global health security. By improving understanding of how novel pathogens emerge, SAGO helps to:

  • Inform public health policies and strategies.
  • Enhance preparedness and response to outbreaks.
  • Support the development of vaccines and therapeutics.

The insights provided by SAGO contribute to the global effort to prevent and control infectious diseases, ultimately protecting human health worldwide.

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Contributors: Prab R. Tumpati, MD