Sebox homeobox
Sebox homeobox is a protein that in humans is encoded by the SEBOX gene. The SEBOX gene is a member of the homeobox family of genes that play crucial roles in gene regulation, cell differentiation, and development.
Function[edit | edit source]
The SEBOX gene encodes a protein that is a member of the homeobox family. Homeobox genes are characterized by a 60-amino acid homeodomain that binds DNA and can regulate the expression of other genes. The encoded protein functions as a transcription factor and may play a role in neurogenesis and endocrine development.
Clinical significance[edit | edit source]
Mutations in the SEBOX gene have been associated with various genetic disorders. For instance, it has been linked to congenital hypothyroidism, a condition characterized by low levels of thyroid hormones at birth, which can lead to growth and developmental problems if not treated.
See also[edit | edit source]
References[edit | edit source]
External links[edit | edit source]
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Contributors: Prab R. Tumpati, MD
