Selepressin

Selepressin is a vasopressin analog that is used in the treatment of vasodilatory shock, a condition that can occur in patients with septic shock. It is a selective V1A receptor agonist, which means it works by stimulating the V1A receptors in the body. This action can help to increase blood pressure and reduce the need for other medications that are used to treat vasodilatory shock.

Mechanism of action

Selepressin works by selectively stimulating the V1A receptor. This receptor is found on the smooth muscle cells of blood vessels, and when it is activated, it causes the blood vessels to constrict. This constriction can help to increase blood pressure in patients with vasodilatory shock.

Uses

Selepressin is primarily used in the treatment of vasodilatory shock, a condition that can occur in patients with septic shock. It can help to increase blood pressure and reduce the need for other medications that are used to treat this condition.

Side effects

As with any medication, selepressin can cause side effects. These can include nausea, vomiting, diarrhea, and abdominal pain. If these side effects become severe or do not go away, patients should contact their healthcare provider.

Contraindications

Selepressin should not be used in patients with a known allergy to the medication. It should also not be used in patients with certain medical conditions, such as heart disease, without first discussing the risks and benefits with a healthcare provider.

See also

• Vasopressin
• Vasodilatory shock
• Septic shock
• V1A receptor

Selepressin Resources
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