Self-protein

Self-protein is a type of protein that is produced by an organism's own cells. These proteins are recognized as "self" by the immune system, which means they are not targeted for destruction. Self-proteins play a crucial role in maintaining homeostasis and preventing autoimmune diseases.

Overview

Self-proteins are a fundamental part of the immune response. They are used by the immune system to distinguish between the body's own cells and foreign cells. This recognition is crucial for the immune system to function properly and to avoid attacking the body's own cells, which can lead to autoimmune diseases.

Role in the Immune System

The immune system uses self-proteins to identify cells that belong to the body. This is done through a process called antigen presentation. In this process, self-proteins are presented on the surface of cells by Major Histocompatibility Complex (MHC) molecules. The immune system recognizes these self-proteins and does not attack the cells presenting them.

Role in Autoimmune Diseases

In some cases, the immune system can mistakenly identify self-proteins as foreign, leading to an attack on the body's own cells. This can result in autoimmune diseases such as rheumatoid arthritis, lupus, and type 1 diabetes. Understanding the role of self-proteins in these diseases can help in the development of treatments.

See Also

• Protein
• Immune system
• Autoimmune diseases
• Antigen presentation
• Major Histocompatibility Complex

References

Self-protein Resources
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