Simons Foundation Autism Research Initiative

Simons Foundation Autism Research Initiative (SFARI) is a research initiative funded by the Simons Foundation to improve the understanding, diagnosis, and treatment of autism spectrum disorders (ASD). Launched in 2003, SFARI's mission is to support innovative research of the highest quality and relevance to ensure a better life for individuals with autism and their families. The initiative emphasizes the development of research resources and collaborations that advance the field of autism research.

Overview

SFARI's approach to autism research is comprehensive, covering a broad spectrum of scientific disciplines including genetics, neuroscience, and psychology. The initiative funds research projects at various stages of development, from basic science to clinical studies. SFARI also supports the development of tools and resources for the autism research community, such as databases and biomaterials, and fosters collaboration among scientists through workshops, conferences, and consortia.

Key Programs and Resources

SFARI Gene

SFARI Gene is an online database that compiles and curates genetic information related to autism spectrum disorders. The database aims to facilitate the understanding of the genetic aspects of ASD by providing a comprehensive, up-to-date resource for researchers.

Autism BrainNet

Autism BrainNet is a network of research institutions that collects, stores, and distributes postmortem brain tissues for the purpose of autism research. This resource enables scientists to study the brain's anatomy and function in relation to ASD, providing critical insights into the disorder.

Simons Simplex Collection (SSC)

The Simons Simplex Collection is a unique and valuable resource for autism research. It consists of genetic and phenotypic data from families that have one child with autism and unaffected parents and siblings. The SSC facilitates studies on the causes and mechanisms of autism, helping to identify potential genetic markers and targets for treatment.

Research Funding

SFARI offers various funding opportunities for autism research, including investigator-initiated grants, pilot awards, and postdoctoral fellowships. The initiative seeks to support innovative projects that have the potential to significantly advance the understanding of autism.

Collaborations and Partnerships

SFARI collaborates with a wide range of stakeholders in the autism community, including researchers, clinicians, and families. The initiative also partners with other organizations and institutions to leverage resources and expertise in pursuit of its mission.

Impact

Since its inception, SFARI has made significant contributions to the field of autism research. The initiative's support has led to important discoveries in the genetics of autism, the development of new research tools and resources, and the advancement of our understanding of the biological basis of ASD. Through its comprehensive approach and commitment to collaboration, SFARI continues to drive progress in autism research and improve outcomes for individuals with autism and their families.