Stigmastanol
(Redirected from Sitostanol)
Stigmastanol is a phytosterol, a type of sterol found in plants. It is a saturated derivative of stigmasterol, which is another plant sterol. Stigmastanol is known for its potential health benefits, particularly in lowering cholesterol levels and improving cardiovascular health.
Chemical Structure and Properties[edit | edit source]
Stigmastanol has a chemical structure similar to that of cholesterol, which allows it to compete with cholesterol for absorption in the digestive system. Its chemical formula is C29H52O, and it has a molecular weight of 416.72 g/mol. The structure includes a sterol backbone with a hydroxyl group at the 3-beta position.
Sources[edit | edit source]
Stigmastanol is found in various plant sources, including vegetable oils, nuts, and seeds. It is also present in smaller amounts in some fruits and vegetables. The highest concentrations are typically found in unrefined plant oils.
Health Benefits[edit | edit source]
Stigmastanol is primarily studied for its role in lowering LDL cholesterol levels. By inhibiting the absorption of cholesterol in the intestines, it can help reduce the overall cholesterol levels in the blood. This can lead to a decreased risk of atherosclerosis and other cardiovascular diseases.
Cholesterol Reduction[edit | edit source]
Stigmastanol competes with dietary cholesterol for absorption in the intestines. This competition reduces the amount of cholesterol that enters the bloodstream, thereby lowering LDL cholesterol levels. Studies have shown that regular consumption of stigmastanol can lead to significant reductions in LDL cholesterol.
Cardiovascular Health[edit | edit source]
By lowering cholesterol levels, stigmastanol can contribute to improved cardiovascular health. Lower cholesterol levels are associated with a reduced risk of heart disease, stroke, and other cardiovascular conditions.
Uses in Food and Supplements[edit | edit source]
Stigmastanol is often added to functional foods and dietary supplements aimed at lowering cholesterol. It is commonly found in margarines, yogurts, and other fortified foods. Supplements containing stigmastanol are also available in the form of capsules and tablets.
Safety and Side Effects[edit | edit source]
Stigmastanol is generally considered safe for consumption. However, excessive intake may lead to gastrointestinal discomfort, such as bloating and diarrhea. It is important to follow recommended dosages and consult with a healthcare provider before starting any new supplement regimen.
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Contributors: Prab R. Tumpati, MD