Small-blue-round-cell tumor

From WikiMD's Wellness Encyclopedia

Small blue round cell tumor (SBRCT) is a term used to describe a group of neoplasms characterized by small, round, relatively undifferentiated cells. They are observed in microscopic examination and are most commonly found in the pediatric population. The group includes Ewing's sarcoma, neuroblastoma, rhabdomyosarcoma, Wilms' tumor, desmoplastic small round cell tumor, and synovial sarcoma.

Classification[edit | edit source]

SBRCTs are classified into the following types:

Diagnosis[edit | edit source]

The diagnosis of SBRCTs is challenging due to their similar histological features. It often requires the use of immunohistochemistry and other advanced techniques such as fluorescence in situ hybridization (FISH) and reverse transcription polymerase chain reaction (RT-PCR).

Treatment[edit | edit source]

Treatment of SBRCTs typically involves a combination of surgery, radiation therapy, and chemotherapy. The choice of treatment depends on the type of SBRCT, its location, and the patient's overall health.

Prognosis[edit | edit source]

The prognosis of SBRCTs varies widely depending on the type of tumor, its location, and the patient's overall health. Some types of SBRCTs, such as Wilms' tumor and neuroblastoma, have relatively good prognoses with appropriate treatment, while others, such as desmoplastic small round cell tumor, have a poorer prognosis.

See also[edit | edit source]

Small-blue-round-cell tumor Resources

Contributors: Prab R. Tumpati, MD