Solitary trichoepithelioma
Solitary Trichoepithelioma is a rare, benign skin tumor that originates from the hair follicle. It is characterized by the presence of a single, small, skin-colored papule that typically appears on the face.
Clinical Presentation[edit | edit source]
Solitary Trichoepithelioma usually presents as a single, small, skin-colored papule that is less than 1 cm in diameter. It is most commonly found on the face, particularly on the nose, cheeks, and forehead. The lesion is typically asymptomatic, but it may occasionally be associated with mild itching or tenderness.
Pathogenesis[edit | edit source]
The exact cause of Solitary Trichoepithelioma is unknown. However, it is believed to be related to mutations in the CYLD gene, which is involved in the regulation of cell growth and differentiation. This mutation leads to the abnormal proliferation of hair follicle cells, resulting in the formation of the tumor.
Diagnosis[edit | edit source]
The diagnosis of Solitary Trichoepithelioma is primarily based on the clinical appearance of the lesion. However, a skin biopsy may be performed to confirm the diagnosis and to rule out other conditions, such as Basal Cell Carcinoma or Trichoblastoma.
Treatment[edit | edit source]
The primary treatment for Solitary Trichoepithelioma is surgical excision. This is usually curative, as the tumor is benign and does not typically recur after removal. However, in some cases, the lesion may be difficult to completely excise due to its location or size.
Prognosis[edit | edit source]
The prognosis for Solitary Trichoepithelioma is generally excellent. The tumor is benign and does not metastasize. However, it may cause cosmetic concerns due to its location on the face.
See Also[edit | edit source]
Solitary trichoepithelioma Resources | |
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Contributors: Prab R. Tumpati, MD