Trichoblastoma
Trichoblastoma[edit | edit source]
Trichoblastoma is a rare, benign skin tumor that originates from the hair follicles. It is considered a type of follicular neoplasm and is often found on the scalp and face.
Presentation[edit | edit source]
Trichoblastomas typically present as solitary, slow-growing nodules. They are usually skin-colored or slightly pigmented and can vary in size. These tumors are most commonly diagnosed in adults, although they can occur at any age.
Histopathology[edit | edit source]
Under the microscope, trichoblastomas are characterized by nests of basaloid cells that resemble the germinal matrix of the hair follicle. The tumor cells are often arranged in a trabecular or ribbon-like pattern. The stroma surrounding the tumor nests is typically fibrous and may contain mucin.
Differential Diagnosis[edit | edit source]
Trichoblastoma must be differentiated from other basaloid tumors such as basal cell carcinoma and trichoepithelioma. Unlike basal cell carcinoma, trichoblastomas do not exhibit peripheral palisading or stromal retraction.
Treatment[edit | edit source]
The primary treatment for trichoblastoma is surgical excision. Complete removal is usually curative, and recurrence is rare. Due to their benign nature, trichoblastomas do not metastasize.
Related Conditions[edit | edit source]
Trichoblastomas are part of a spectrum of follicular tumors that include trichoepithelioma and pilomatricoma. These tumors share a common origin from the hair follicle but differ in their clinical and histological features.
Related Pages[edit | edit source]
References[edit | edit source]
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Trichoblastoma: a distinctive neoplasm derived from the hair follicle, Journal of Cutaneous Pathology, 1992, Vol. 19(Issue: 5), pp. 329-334, DOI: 10.1111/j.1600-0560.1992.tb01312.x,
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Lever's Histopathology of the Skin, 10th edition, Lippincott Williams & Wilkins, 2009, ISBN 978-0781773634,
Trichoblastoma
Micrographs of trichoblastoma
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