Pentoxyverine

Overview of the antitussive medication Pentoxyverine

Pentoxyverine

Chemical structure of Pentoxyverine

Pentoxyverine, also known as carbetapentane, is a medication used primarily as an antitussive (cough suppressant). It is commonly used to relieve coughs associated with colds, bronchitis, and other respiratory conditions. Pentoxyverine is available in various formulations, including syrups and tablets.

Pharmacology

Pentoxyverine acts on the central nervous system to suppress the cough reflex. It is believed to exert its effects by acting on the medulla oblongata, the part of the brain responsible for controlling the cough reflex. Unlike opioid cough suppressants, pentoxyverine does not have significant narcotic effects, making it a safer alternative for patients who may be at risk of opioid addiction.

Mechanism of Action

The exact mechanism of action of pentoxyverine is not fully understood. However, it is thought to involve the inhibition of the cough center in the brain. Pentoxyverine may also have mild anticholinergic properties, which can contribute to its cough-suppressing effects.

Side Effects

Common side effects of pentoxyverine include drowsiness, dizziness, and gastrointestinal disturbances such as nausea and vomiting. In rare cases, it may cause allergic reactions or skin rash. Patients are advised to avoid operating heavy machinery or driving while taking pentoxyverine due to its potential to cause drowsiness.

Contraindications

Pentoxyverine should not be used in patients with known hypersensitivity to the drug. It is also contraindicated in patients with asthma or other respiratory conditions where suppression of the cough reflex could be harmful. Caution is advised in patients with glaucoma or prostatic hypertrophy due to its anticholinergic effects.

Dosage and Administration

Pentoxyverine is typically administered orally. The dosage varies depending on the formulation and the age of the patient. It is important to follow the prescribed dosage and not to exceed the recommended amount to avoid potential side effects.

Related pages

• Antitussive
• Cough
• Respiratory system
• Central nervous system