Somatorelin

Somatorelin is a synthetic form of growth hormone-releasing hormone (GHRH), which is used primarily as a diagnostic agent in the assessment of growth hormone secretion. Somatorelin functions by stimulating the pituitary gland to release growth hormone, which is crucial for growth and metabolism.

Medical Uses

Somatorelin is used in the diagnosis of growth hormone deficiency and in evaluating the function of the pituitary gland. It is administered through an injection and observed for the response of growth hormone levels in the blood.

Mechanism of Action

Somatorelin works by mimicking the natural growth hormone-releasing hormone that stimulates the pituitary gland. This leads to an increase in growth hormone secretion from the anterior pituitary gland. The response of growth hormone to somatorelin can help determine the health and functionality of the pituitary gland.

Pharmacokinetics

Details on the pharmacokinetics of somatorelin, such as absorption, metabolism, and excretion, are not extensively documented. However, as a peptide, it is likely to be metabolized by peptidases and cleared primarily by renal and hepatic pathways.

Side Effects

The administration of somatorelin may cause side effects typical of agents that stimulate growth hormone release, such as pain at the injection site, headaches, and symptoms associated with changes in growth hormone levels.

Regulatory Status

Somatorelin is available under prescription and is regulated by health authorities to ensure its safe and effective use in diagnostic settings.