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Ras-related protein
...mal cellular growth, differentiation, and development. See ras superfamily protein

281 bytes (31 words) - 14:00, 8 April 2024
Enzyme superfamily
'''Enzyme superfamily‏‎''' ...reaction|reaction]]. Despite their diverse functions, members of an enzyme superfamily share a common [[catalytic mechanism]] or a common structural feature that

2 KB (313 words) - 22:42, 28 February 2024
Mucrocetin
...gene is a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. ...mmation and immune response. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region.

1 KB (145 words) - 08:14, 24 February 2024
TNFRSF1A
...apoptosis]], and functioning as a regulator of inflammation. Antiapoptotic protein [[BCL2]] has been shown to be a regulator of this receptor's signaling path The protein encoded by the TNFRSF1A gene is a receptor for [[tumor necrosis factor]] (T

1 KB (190 words) - 20:57, 25 February 2024
TNFRSF19
...known as '''TROY''', is a member of the [[TNF-receptor superfamily]]. This protein is highly expressed in [[nervous tissue]] and plays a crucial role in the [ ...repeat]], a common structural motif found in proteins of the TNF-receptor superfamily. The TNFR-Cys repeat is involved in ligand binding and receptor multimeriza

1 KB (172 words) - 05:59, 10 March 2024
IGLL1
...he IGLL1 [[gene]]. This protein is a member of the [[immunoglobulin]] gene superfamily and is located in the [[chromosome]] 22 region, which is associated with [[ The IGLL1 protein is a surrogate light chain that plays a central role in early [[B cell]] de

1 KB (149 words) - 22:56, 25 February 2024
GDF5
...polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. ...ins. It is expressed in long bones during human embryonic development. The protein plays a key role in the formation of [[morphogenesis|morphogenetic]] featur

2 KB (204 words) - 21:07, 10 March 2024
GDF2
...tein]] (BMP) family and the [[TGF-beta superfamily]]. The proteins of this superfamily are highly diverse in function and play crucial roles in a variety of biolo ...is a secreted ligand of the [[TGF-beta]] (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading

2 KB (249 words) - 13:00, 10 March 2024
Neogenin
...rus-top}}<br>a member of the immunoglobulin superfamily and related to DCC protein; amino acid sequence in first source; GenBank U07644

194 bytes (24 words) - 00:39, 5 April 2024
CD155
...umans is encoded by the CD155 gene. It is a member of the [[immunoglobulin superfamily]] and mediates cell adhesion with other cells. CD155 is also a receptor for CD155 is a transmembrane protein that is part of the [[immunoglobulin superfamily]]. It is involved in cell adhesion and in the immune response. CD155 is als

1 KB (198 words) - 21:41, 25 February 2024
IgSF
...adhesion processes of cells. Molecules are categorized as members of this superfamily based on shared structural features with immunoglobulins (also known as ant ...o sheets of antiparallel beta strands. The immunoglobulin fold is a common protein folding pattern in the molecular evolution of proteins.

2 KB (224 words) - 22:29, 25 February 2024
Major facilitator superfamily domain containing 2b
{{dict-top}}<br>Major facilitator superfamily domain containing 2B is a protein that in humans is encoded by the MFSD2B gene [[Category:Dictionary of medic

190 bytes (27 words) - 10:20, 21 March 2024
SIRPB1
...s is encoded by the SIRPB1 gene. It is a member of the [[signal-regulatory protein]] (SIRP) family, and also known as SIRP-beta-1. ...tein is a transmembrane protein that is composed of three [[immunoglobulin superfamily]] domains, a single transmembrane region, and a cytoplasmic tail. The extra

2 KB (198 words) - 06:05, 10 March 2024
TNFRSF13B
...e TNFRSF13B gene. It is a member of the [[tumor necrosis factor receptor]] superfamily. ...It interacts with [[calcium-modulator and cyclophilin ligand]] (CAML). The protein plays a crucial role in [[B-cell]] development and autoimmune disease. Muta

1 KB (169 words) - 21:40, 25 February 2024
Ras p21 protein activator 2
...tivating protein]] (GAP) family, which function as modulators of the [[Ras superfamily]] of proteins. ...s protein]]. It converts active Ras-GTP to the inactive form Ras-GDP. This protein is crucial in cellular signaling pathways, controlling cell growth, differe

1 KB (195 words) - 08:11, 10 March 2024
MFSD8
...d by the MFSD8 [[gene]]. This protein is a member of the major facilitator superfamily, a diverse group of proteins that transport small solutes in response to ch The MFSD8 protein is a [[lysosomal]] protein that is involved in the transport of lipids. It is particularly important i

2 KB (226 words) - 06:16, 10 March 2024
Vascular endothelial growth inhibitor
...ily member 15 (251 aa, ~28 kda) is encoded by the human tnfsf15 gene. This protein plays a role in both the inhibition of angiogenesis and the induction of ap

257 bytes (35 words) - 01:13, 21 March 2024
GDF6
...polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. * [[Bone morphogenetic protein]]

2 KB (222 words) - 12:28, 10 March 2024
Immunoglobulin superfamily
...adhesion processes of cells. Molecules are categorized as members of this superfamily based on shared structural features with immunoglobulins (also known as ant Immunoglobulin-like domains are one of the most common protein modules, and are characterized by 70-110 amino-acid residues. They are ofte

2 KB (205 words) - 03:13, 22 February 2024
Death receptor 4
...SF10A'' [[gene]]. It is a member of the [[tumor necrosis factor]] receptor superfamily, and is also known as TRAIL receptor 1 (TRAILR1) and TNF-related apoptosis- ...containing adaptor protein, is required for the apoptosis mediated by this protein.

1 KB (195 words) - 15:51, 22 February 2024