Spiraviridae

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Spiraviridae is a family of viruses that infect bacteria, specifically archaea. The family name is derived from the Latin spiraviridae, meaning "spiral viruses", due to the unique spiral shape of the viruses in this family.

Taxonomy[edit | edit source]

The family Spiraviridae is part of the order Ligamenvirales, which also includes the families Lipothrixviridae and Tristromaviridae. The family Spiraviridae is further divided into two genera: Alphaspiravirus and Betaspiravirus. Each genus contains several species of viruses.

Structure and Genome[edit | edit source]

Viruses in the Spiraviridae family are non-enveloped and have a unique spiral shape, which is where the family gets its name. The viral genome is linear, double-stranded DNA, and is approximately 20-30 kilobases in length. The genome encodes for several proteins, including a DNA polymerase and a capsid protein.

Life Cycle[edit | edit source]

The life cycle of Spiraviridae viruses begins with the virus attaching to the host cell using specific receptor proteins on the cell surface. The virus then injects its DNA into the host cell, where it is replicated using the host's cellular machinery. The newly synthesized viral proteins and DNA are then assembled into new virus particles, which are released from the host cell to infect other cells.

Pathogenicity[edit | edit source]

Spiraviridae viruses are not known to cause disease in humans or animals. They are strictly bacteriophages, meaning they infect and replicate within bacteria. The host range of Spiraviridae viruses is limited to certain species of archaea.

Research and Applications[edit | edit source]

Research on Spiraviridae viruses has contributed to our understanding of virus-host interactions and the evolution of viruses. In addition, Spiraviridae viruses have potential applications in biotechnology, such as the development of new antibiotics and gene therapy vectors.

See Also[edit | edit source]

References[edit | edit source]

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Contributors: Prab R. Tumpati, MD