Spondyloarthropathy
(Redirected from Spondarthritis)
Spondyloarthropathy[edit | edit source]
Spondyloarthropathy or spondyloarthrosis refers to a group of joint diseases that primarily affect the vertebral column. These conditions are characterized by inflammation and can lead to significant pain and disability. They encompass a range of disorders, including but not limited to psoriatic arthritis, Ankylosing spondylitis, and forms of rheumatoid arthritis.
Related terms[edit | edit source]
- spondylopathy is a disease of the vertebra
- Spondyloarthropathy with inflammation is called axial spondyloarthritis
Signs and symptoms[edit | edit source]
Non-vertebral signs and symptoms is back pain which is unique because it decreases with activity.
Seronegative spondyloarthropathy[edit | edit source]
Seronegative spondyloarthropathy (or seronegative spondyloarthritis) is a group of diseases involving the axial skeleton
"Seronegative" refers to the fact that these diseases are negative for rheumatoid factor
Types of Spondyloarthropathy[edit | edit source]
Spondyloarthropathies can be classified into several main types, each with distinct characteristics:
- Ankylosing Spondylitis: A chronic inflammatory disease that primarily affects the spine and sacroiliac joints.
- Psoriatic Arthritis: Associated with the skin condition psoriasis, this type can affect the spine in addition to other joints.
- Enteropathic Arthritis: Arthritis that is associated with inflammatory bowel diseases like Crohn's disease and ulcerative colitis.
- Reactive Arthritis: Arthritis that occurs as a reaction to an infection elsewhere in the body.
Symptoms[edit | edit source]
Common symptoms of spondyloarthropathies include:
- Chronic back pain and stiffness, often worse in the morning or after periods of inactivity.
- Pain and swelling in other joints, depending on the specific type.
- In severe cases, a reduction in spinal flexibility and overall mobility.
Diagnosis[edit | edit source]
Diagnosis of spondyloarthropathy involves:
- Clinical evaluation of symptoms.
- Imaging tests such as X-rays, MRI, and CT scans to detect changes in joints and bones.
- Blood tests to identify markers of inflammation and genetic markers associated with specific types.
Treatment[edit | edit source]
Treatment for spondyloarthropathies aims to manage symptoms and prevent or slow disease progression. Options include:
- Medications: Including nonsteroidal anti-inflammatory drugs (NSAIDs), disease-modifying antirheumatic drugs (DMARDs), and biologics.
- Physical Therapy: To maintain joint flexibility and muscle strength.
- Lifestyle Modifications: Such as regular exercise and maintaining a healthy weight.
Conditions[edit | edit source]
The following conditions are typically included within the group of seronegative spondylarthropathies:
Condition | Percent of people with the condition who are HLA-B27 positive |
---|---|
Axial spondyloarthritis (including ankylosing spondylitis)[1][2] |
|
Reactive arthritis[1][2] (formerly known as Reiter's syndrome) | 60–80% |
Enteropathic arthropathy or spondylitis associated with inflammatory bowel disease[1][2] (including Crohn's disease and ulcerative colitis) |
60% |
Psoriatic arthritis[1][2] | 40–50% |
Isolated acute anterior uveitis | 50% |
Juvenile idiopathic arthritis (subtype: late-onset oligoarticular JIA) | |
Undifferentiated spondyloarthropathy[1][2] (USpA) | 20–25% |
Spondyloarthropathy Resources | |
---|---|
|
Prognosis[edit | edit source]
The prognosis for individuals with spondyloarthropathy varies depending on the type and severity of the condition. Early diagnosis and treatment are key to managing symptoms and maintaining quality of life.
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