Stereotaxic atlas
Sonodynamic therapy (SDT) is a form of ultrasound therapy in which ultrasound waves are used in conjunction with chemotherapeutic drugs or radiosensitizers to enhance the effects of the drugs. This therapy is primarily used in the treatment of cancer and other diseases.
Mechanism of Action[edit | edit source]
The mechanism of action of sonodynamic therapy involves the use of ultrasound waves to enhance the effects of chemotherapeutic drugs or radiosensitizers. The ultrasound waves are believed to increase the permeability of cell membranes, allowing the drugs to enter the cells more easily. This can enhance the effectiveness of the drugs and potentially reduce the amount of drug needed for treatment.
Applications[edit | edit source]
Sonodynamic therapy has been used in the treatment of various types of cancer, including breast cancer, lung cancer, and prostate cancer. It has also been used in the treatment of other diseases, such as Alzheimer's disease and Parkinson's disease.
Advantages[edit | edit source]
One of the main advantages of sonodynamic therapy is that it can potentially reduce the amount of chemotherapeutic drugs needed for treatment. This can reduce the side effects associated with these drugs. Additionally, because ultrasound waves can penetrate deep into tissues, sonodynamic therapy can be used to treat tumors that are difficult to reach with other forms of treatment.
Disadvantages[edit | edit source]
While sonodynamic therapy has many potential benefits, it also has some disadvantages. One of the main disadvantages is that the effects of the therapy can be difficult to predict. This is because the effects of the ultrasound waves can vary depending on the specific characteristics of the tumor and the surrounding tissues. Additionally, while the therapy can potentially reduce the amount of drug needed for treatment, it can also potentially increase the risk of drug resistance.
Future Research[edit | edit source]
Future research in sonodynamic therapy is focused on improving the predictability and effectiveness of the therapy. This includes research into the specific mechanisms of action of the therapy, as well as research into new drugs and radiosensitizers that can be used in conjunction with the ultrasound waves.
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Contributors: Prab R. Tumpati, MD
