Sterile talc powder

What is Sterile talc powder?[edit | edit source]

Sterile talc powder (Sclerosol Intrapleural Aerosol; Sterile Talc Powder; Steritalc) is a sclerosing agent used to prevent malignant pleural effusions from recurring (coming back).

Talc

Talc to

Talc structure

What are the uses of this medicine?[edit | edit source]

Sterile talc powder (Sclerosol Intrapleural Aerosol; Sterile Talc Powder; Steritalc) is used to prevent pleural effusions (an abnormal collection of fluid in the space between the lungs and the chest wall).
Sterile talc powder is inserted into the space, causing it to close up, so fluid cannot collect there.

How does this medicine work?[edit | edit source]

Talc is in a class of medications called sclerosing agents.
It works by irritating the lining of the chest cavity so that the cavity closes and there is no space for fluid.

Who Should Not Use this medicine ?[edit | edit source]

This medicine have no usage limitations.

What drug interactions can this medicine cause?[edit | edit source]

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

Is this medicine FDA approved?[edit | edit source]

STERILE TALC POWDER (talc), for intrapleural use was approved in the year of 2003.

How should this medicine be used?[edit | edit source]

Recommended dosage:

The recommended dose is 5 g, dissolved in 50 ml to 100 ml 0.9% Sodium Chloride Injection, USP , administered intrapleurally.

Administration:

Talc comes as a powder to be mixed with liquid and placed in the chest cavity through a chest tube, and as an aerosol to be sprayed through a tube into the chest cavity during surgery.
Talc is given by a doctor in a hospital.
After your doctor places talc in your chest cavity, you may be asked to change positions every 20-30 minutes for several hours to allow the talc to spread through your chest cavity.

What are the dosage forms and brand names of this medicine?[edit | edit source]

This medicine is available in fallowing doasage form:

As 5 g powder in a single-dose bottle, for suspension

This medicine is available in fallowing brand namesː

Sclerosol Intrapleural Aerosol; Sterile Talc Powder; Steritalc

What side effects can this medication cause?[edit | edit source]

The most common side effects of this medicine include:

fever
pain
bleeding in the area where the chest tube was inserted

Some side effects can be serious which may include:

fever
shortness of breath
coughing up blood
fast heartbeat
chest pain or pressure
dizziness
fainting

What special precautions should I follow?[edit | edit source]

Acute Pneumonitis and ARDS, including fatal cases, occur with intrapleural talc administration.
Sclerosis of the pleural space may preclude or complicate subsequent ipsilateral surgery and diagnostic procedures. Consider the possible effects of the use of Sterile Talc Powder on future diagnostic and therapeutic procedures prior to administration.
Advise patients to notify their healthcare provider if new or worsening pulmonary symptoms develop.

What to do in case of emergency/overdose?[edit | edit source]

In case of overdose, call the poison control helpline of your country. In the United States, call 1-800-222-1222.

Overdose related information is also available online at poisonhelp.org/help.
In the event that the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services. In the United States, call 911.

Can this medicine be used in pregnancy?[edit | edit source]

There are no adequate and well-controlled studies in pregnant women.
Sterile talc powder should be used during pregnancy only if clearly needed.

Can this medicine be used in children?[edit | edit source]

Safety and effectiveness have not been established in pediatric patients.

What are the active and inactive ingredients in this medicine?[edit | edit source]

Active Ingredient:

Talc

Inactive Ingredients:

none

Who manufactures and distributes this medicine?[edit | edit source]

Distributed by:

Bryan Corporation. Woburn, MA

What should I know about storage and disposal of this medication?[edit | edit source]

Store the powder at 25°C (77°F); excursions permitted between15°C to 30°C (59°F - 86°F).
Protect against sunlight.

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