Strophanthus kombe

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A plant species used in traditional medicine and as a source of arrow poison


Overview[edit | edit source]

Strophanthus kombe plant

Strophanthus kombe is a species of flowering plant in the family Apocynaceae. It is native to tropical regions of Africa, where it is found in countries such as Tanzania, Mozambique, and Malawi. The plant is known for its medicinal properties and its use as a source of arrow poison.

Description[edit | edit source]

Strophanthus kombe is a climbing shrub or liana that can grow up to 10 meters in length. The leaves are opposite, simple, and elliptical, with a glossy green appearance. The flowers are tubular and fragrant, with a distinctive star-like shape, and are typically white or pale yellow with purple streaks.

Chemical Composition[edit | edit source]

The seeds of Strophanthus kombe contain potent cardiac glycosides, primarily ouabain and strophanthin. These compounds have a strong effect on the heart, increasing the force of contraction and slowing the heart rate. Due to these properties, they have been used in traditional medicine and in the development of certain cardiac drugs.

Traditional Uses[edit | edit source]

In traditional African medicine, Strophanthus kombe has been used for its cardiotonic effects. The seeds are sometimes used to treat heart conditions and as a diuretic. Additionally, the plant is famously known for its use as an arrow poison by various African tribes. The seeds are crushed and applied to arrow tips, which can be lethal when used for hunting.

Pharmacological Applications[edit | edit source]

The cardiac glycosides derived from Strophanthus kombe have been studied for their potential therapeutic applications. Ouabain, in particular, has been investigated for its use in treating heart failure and certain arrhythmias. However, due to its narrow therapeutic index and potential toxicity, its use is limited and requires careful medical supervision.

Cultivation and Harvesting[edit | edit source]

Strophanthus kombe is typically found in forested areas and along riverbanks. It prefers well-drained soils and a warm, humid climate. The seeds are harvested when ripe and must be handled with care due to their toxic properties.

Conservation Status[edit | edit source]

While not currently listed as endangered, the habitat of Strophanthus kombe is subject to pressures from deforestation and land conversion. Conservation efforts are important to ensure the sustainability of this species and its continued availability for medicinal use.

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Contributors: Prab R. Tumpati, MD