Subthalamic fasciculus

Subthalamic fasciculus is a part of the human brain that is involved in the regulation of movement. It is a component of the basal ganglia, a group of nuclei located deep within the cerebral hemispheres.

Etymology[edit | edit source]

The term "subthalamic" is derived from the Latin words "sub" meaning under, and "thalamus" meaning inner chamber. The term "fasciculus" is derived from the Latin word "fasciculus" meaning small bundle. Thus, "subthalamic fasciculus" refers to a small bundle of nerve fibers located beneath the thalamus.

Anatomy[edit | edit source]

The subthalamic fasciculus is a white matter tract that connects the subthalamic nucleus and the globus pallidus. It is part of the internal capsule, a white matter structure situated in the inferomedial part of each cerebral hemisphere of the brain.

Function[edit | edit source]

The subthalamic fasciculus plays a crucial role in the regulation of movement. It is involved in the transmission of signals from the subthalamic nucleus to the globus pallidus, which are key components of the basal ganglia circuitry. This circuitry is responsible for the control of voluntary movements and the regulation of muscle tone.

Clinical significance[edit | edit source]

Damage to the subthalamic fasciculus can result in movement disorders such as Parkinson's disease and Huntington's disease. These disorders are characterized by a loss of control over voluntary movements, leading to symptoms such as tremors, rigidity, and bradykinesia (slowness of movement).

See also[edit | edit source]

Subthalamic fasciculus Resources
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