Sulfachlorpyridazine

Sulfachlorpyridazine is an antibiotic used primarily in veterinary medicine. It is a type of sulfonamide, a class of drugs that inhibit the growth of bacteria by preventing them from synthesizing folic acid, an essential nutrient. Sulfachlorpyridazine is used to treat a variety of bacterial infections in animals, including those caused by E. coli, Salmonella, and Streptococcus.

History

Sulfachlorpyridazine was first synthesized in the 1940s as part of a broader effort to develop effective antibiotics. It was one of many sulfonamides developed during this period, which also saw the introduction of sulfadiazine, sulfamethoxazole, and sulfisoxazole.

Pharmacology

Sulfachlorpyridazine works by inhibiting the enzyme dihydropteroate synthase, which is necessary for the synthesis of folic acid in bacteria. By blocking this enzyme, sulfachlorpyridazine prevents bacteria from growing and multiplying.

Uses

Sulfachlorpyridazine is used in veterinary medicine to treat a variety of bacterial infections. It is particularly effective against E. coli, Salmonella, and Streptococcus, and is often used to treat infections in poultry and swine.

Side Effects

Like all drugs, sulfachlorpyridazine can cause side effects. These may include allergic reactions, digestive problems, and skin reactions. In rare cases, it can cause serious side effects such as anemia, thrombocytopenia, and leukopenia.

See Also

• Sulfonamide
• Antibiotic
• Veterinary medicine

Sulfachlorpyridazine Resources
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