Sulfadimethoxine
Sulfadimethoxine is a long-lasting sulfonamide antimicrobial medication used in veterinary medicine. It is used to treat many infections, including respiratory, urinary tract, enteric, and soft tissue infections.
Pharmacology[edit | edit source]
Sulfadimethoxine inhibits bacterial synthesis of folic acid, which is essential for the growth and reproduction of bacteria. It is a competitive inhibitor of para-aminobenzoic acid (PABA), which is required by bacteria to synthesize folic acid.
Veterinary Use[edit | edit source]
In veterinary medicine, sulfadimethoxine is used to treat a variety of infections. It is commonly used in the treatment of coccidiosis, a parasitic disease of the intestinal tract. It is also used to treat fowl cholera, avian malaria, and infectious coryza in poultry.
Side Effects[edit | edit source]
Like other sulfonamides, sulfadimethoxine can cause a variety of side effects. These can include anemia, leukopenia, thrombocytopenia, and hypersensitivity reactions. In rare cases, it can cause crystalluria, which can lead to kidney damage.
Regulatory Status[edit | edit source]
In the United States, sulfadimethoxine is approved by the Food and Drug Administration (FDA) for use in chickens, turkeys, and dogs. It is not approved for use in humans.
See Also[edit | edit source]
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