Suptavumab
Suptavumab (also known as REGN2222) is a monoclonal antibody designed for the prevention of respiratory syncytial virus (RSV) infections. It was developed by Regeneron Pharmaceuticals but failed in Phase 3 clinical trials.
History[edit | edit source]
Suptavumab was developed by Regeneron Pharmaceuticals as a potential treatment for respiratory syncytial virus (RSV) infections. The drug was designed to bind to the RSV F protein, a fusion protein that allows the virus to enter host cells. By binding to this protein, suptavumab was intended to prevent the virus from infecting cells.
In 2017, Regeneron announced that suptavumab had failed in Phase 3 clinical trials. The drug did not significantly reduce the incidence of medically-attended RSV infections in infants, which was the primary endpoint of the trial.
Mechanism of Action[edit | edit source]
Suptavumab is a monoclonal antibody that targets the RSV F protein. This protein is essential for the virus's ability to infect host cells. By binding to the F protein, suptavumab was designed to prevent the virus from entering cells and causing an infection.
Clinical Trials[edit | edit source]
Suptavumab underwent Phase 3 clinical trials to test its efficacy in preventing RSV infections in infants. However, the drug did not meet its primary endpoint, which was a reduction in the incidence of medically-attended RSV infections.
Future Development[edit | edit source]
Following the failure of suptavumab in clinical trials, Regeneron has not announced any plans to continue its development.
See Also[edit | edit source]
References[edit | edit source]
| Suptavumab Resources | |
|---|---|
|
 |
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
