Systemic administration
Systemic administration is a route of administration of medication that results in the active substance being distributed throughout the entire body. This is in contrast to topical administration, which targets a specific area of the body, or local administration, which targets a specific organ or tissue.
Methods of Systemic Administration[edit | edit source]
There are several methods of systemic administration, each with its own advantages and disadvantages. These include:
- Oral administration: This is the most common method of systemic administration. The medication is swallowed and absorbed through the gastrointestinal tract. This method is convenient and non-invasive, but the medication may be affected by stomach acid or food in the stomach.
- Intravenous administration: This method involves injecting the medication directly into a vein. It allows for rapid distribution of the medication throughout the body, but it is invasive and carries a risk of infection.
- Intramuscular administration: This method involves injecting the medication into a muscle. The medication is absorbed into the bloodstream more slowly than with intravenous administration, but it can be used for larger volumes of medication.
- Subcutaneous administration: This method involves injecting the medication under the skin. It is used for medications that need to be absorbed slowly over a long period of time.
- Inhalation administration: This method involves inhaling the medication into the lungs. It is used for medications that need to reach the lungs quickly, such as asthma medications.
Pharmacokinetics of Systemic Administration[edit | edit source]
The pharmacokinetics of systemic administration involves several stages:
- Absorption: This is the process by which the medication moves from the site of administration into the bloodstream.
- Distribution: This is the process by which the medication is transported throughout the body.
- Metabolism: This is the process by which the body breaks down the medication.
- Excretion: This is the process by which the body removes the medication.
See Also[edit | edit source]
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