Systemic administration

From WikiMD's Wellness Encyclopedia

Systemic administration is a route of administration of medication that results in the active substance being distributed throughout the entire body. This is in contrast to topical administration, which targets a specific area of the body, or local administration, which targets a specific organ or tissue.

Methods of Systemic Administration[edit | edit source]

There are several methods of systemic administration, each with its own advantages and disadvantages. These include:

  • Oral administration: This is the most common method of systemic administration. The medication is swallowed and absorbed through the gastrointestinal tract. This method is convenient and non-invasive, but the medication may be affected by stomach acid or food in the stomach.
  • Intravenous administration: This method involves injecting the medication directly into a vein. It allows for rapid distribution of the medication throughout the body, but it is invasive and carries a risk of infection.
  • Intramuscular administration: This method involves injecting the medication into a muscle. The medication is absorbed into the bloodstream more slowly than with intravenous administration, but it can be used for larger volumes of medication.
  • Subcutaneous administration: This method involves injecting the medication under the skin. It is used for medications that need to be absorbed slowly over a long period of time.
  • Inhalation administration: This method involves inhaling the medication into the lungs. It is used for medications that need to reach the lungs quickly, such as asthma medications.

Pharmacokinetics of Systemic Administration[edit | edit source]

The pharmacokinetics of systemic administration involves several stages:

  • Absorption: This is the process by which the medication moves from the site of administration into the bloodstream.
  • Distribution: This is the process by which the medication is transported throughout the body.
  • Metabolism: This is the process by which the body breaks down the medication.
  • Excretion: This is the process by which the body removes the medication.

See Also[edit | edit source]


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