TACE

TACE or Transarterial chemoembolization is a minimally invasive procedure performed in interventional radiology to restrict a tumor's blood supply. Small embolic particles coated with chemotherapy drugs are injected to selectively occlude the tumor's blood supply, thereby depriving the tumor of necessary nutrients and oxygen. This procedure is commonly used to treat primary liver cancer, also known as Hepatocellular carcinoma (HCC).

Procedure

The procedure is performed under local anesthesia. A small incision is made in the groin area, and a catheter is inserted into the femoral artery. Using fluoroscopy, the catheter is guided to the hepatic artery, which supplies blood to the liver and the tumor. The chemotherapy-coated particles are then injected into the artery. The particles embolize, or block, the small blood vessels and deliver the chemotherapy drugs directly to the tumor.

Indications

TACE is primarily indicated for patients with Hepatocellular carcinoma (HCC), especially those who are not suitable candidates for surgery or ablation therapies. It may also be used in patients with metastatic liver disease.

Risks and Complications

As with any procedure, TACE carries some risks. These may include infection, bleeding, damage to the liver or other organs, and reactions to the anesthesia or chemotherapy drugs. Some patients may experience post-embolization syndrome, which includes symptoms such as fever, abdominal pain, and nausea.

Effectiveness

Studies have shown that TACE can improve survival rates for patients with HCC. However, the effectiveness of the procedure can vary depending on the size and location of the tumor, the patient's overall health, and the specific chemotherapy drugs used.

See Also

• Hepatocellular carcinoma
• Interventional radiology
• Chemotherapy
• Embolization

TACE Resources
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