TAS2R39

TAS2R39 is a gene that provides instructions for making a protein that is part of the bitter taste receptor family. This protein is found in taste bud cells on the tongue and in the back of the mouth. The TAS2R39 protein is specifically involved in the perception of bitter taste.

Function

The TAS2R39 gene belongs to the TAS2R gene family, which is responsible for the encoding of bitter taste receptors. These receptors are located on the surface of taste receptor cells and are activated by a variety of bitter compounds. When activated, these receptors send signals to the brain that are interpreted as a bitter taste.

The TAS2R39 gene is thought to play a role in the detection of certain bitter compounds found in foods such as broccoli, Brussels sprouts, and coffee. Variations in this gene may affect an individual's sensitivity to these compounds, potentially influencing dietary choices and nutritional status.

Genetic Variations

Several genetic variations in the TAS2R39 gene have been identified. These variations can affect the function of the TAS2R39 protein and may influence an individual's perception of bitter taste. Some studies suggest that individuals with certain variations in the TAS2R39 gene may be more sensitive to bitter tastes, while others may be less sensitive.

Clinical Significance

Understanding the function of the TAS2R39 gene and its variations may have implications for nutrition and dietary behavior. For example, individuals who are more sensitive to bitter tastes may be less likely to consume certain healthy but bitter-tasting foods, potentially affecting their nutritional status.

Further research is needed to fully understand the role of the TAS2R39 gene in taste perception and dietary behavior, as well as potential implications for health and disease.