TAS2R60

TAS2R60 is a protein that in humans is encoded by the TAS2R60 gene. It is a member of the bitter taste receptor family, which is a group of G protein-coupled receptors. These receptors are specifically located on the taste buds in the mouth and are responsible for the perception of bitter taste.

Function

The TAS2R60 protein is a taste receptor, specifically a bitter taste receptor. It is one of the 25 human bitter taste receptors and is encoded by the TAS2R60 gene. The protein is expressed in the taste buds on the tongue and is responsible for the perception of a variety of bitter compounds.

Gene

The TAS2R60 gene is located on chromosome 12 in humans. It is part of a cluster of similar taste receptor genes on this chromosome. The gene is approximately 1,000 base pairs long and consists of a single exon.

Clinical significance

Variations in the TAS2R60 gene have been associated with individual differences in taste perception, particularly the perception of bitter taste. Some studies have suggested that these variations may influence dietary habits and potentially health outcomes. For example, individuals with certain variations in the TAS2R60 gene may find certain foods, such as vegetables, more bitter and therefore less palatable, potentially leading to a lower intake of these foods.

See also

• Taste receptor
• Bitter taste
• G protein-coupled receptor
• Chromosome 12