THQ-PINACA
THQ-PINACA is a synthetic cannabinoid that is derived from cannabinoids in cannabis plants. It is a member of the indazole family of cannabinoids and is known for its potent psychoactive effects.
History[edit | edit source]
THQ-PINACA was first identified in 2013 by the European Monitoring Centre for Drugs and Drug Addiction (EMCDDA). It was found in herbal smoking blends in Japan and has since been detected in various parts of the world.
Pharmacology[edit | edit source]
Like other synthetic cannabinoids, THQ-PINACA acts as a full agonist at the CB1 receptor, which is predominantly found in the brain. This is in contrast to THC, the main psychoactive component in cannabis, which is a partial agonist at the CB1 receptor. The full agonist activity of THQ-PINACA is thought to be responsible for its potent psychoactive effects, which can be several times stronger than those of THC.
Legal status[edit | edit source]
The legal status of THQ-PINACA varies by country. In the United States, it is a Schedule I controlled substance. In the European Union, it is a controlled substance under the Psychoactive Substances Act.
Health effects[edit | edit source]
The health effects of THQ-PINACA are not well-studied, but it is known to be potentially harmful. It can cause severe intoxication and has been associated with numerous hospitalizations and deaths. Symptoms of intoxication can include agitation, rapid heart rate, vomiting, and seizures. Long-term effects are unknown.
See also[edit | edit source]
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Contributors: Prab R. Tumpati, MD
