TMEM229B

TMEM229 b

File:T139 phosphorylation site.JPG

T139 phosphorylation site

File:Connexin subunit.jpg

Connexin subunit

TMEM229B is a protein that in humans is encoded by the TMEM229B gene. This gene is located on chromosome 17. The function of TMEM229B is not well understood, but it is a member of the transmembrane protein family, which typically spans the cell membrane and is involved in various cellular processes.

Structure

The TMEM229B protein is characterized by multiple transmembrane domains, which allow it to integrate into the lipid bilayer of the cell membrane. The exact number of transmembrane domains and the topology of TMEM229B are subjects of ongoing research.

Function

The precise biological function of TMEM229B remains to be fully elucidated. However, proteins in the transmembrane family are often involved in signal transduction, transport of molecules across the membrane, and maintaining the structural integrity of the cell membrane.

Expression

TMEM229B is expressed in various tissues, although the levels of expression and the specific tissues where it is most active are still being studied. Expression patterns can provide clues to the protein's function and its role in different physiological processes.

Clinical Significance

Mutations or dysregulation of the TMEM229B gene may be associated with certain diseases, although specific conditions linked to TMEM229B have not been conclusively identified. Further research is needed to determine any potential clinical implications of TMEM229B.

Research

Ongoing research aims to better understand the role of TMEM229B in cellular processes and its potential involvement in disease. Studies often focus on gene expression analysis, protein interaction networks, and functional assays to uncover the biological significance of TMEM229B.

Related Pages

• Transmembrane protein
• Chromosome 17
• Signal transduction
• Cell membrane
• Gene expression