Tabun (nerve agent)

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Tabun or GA is a chemical compound that is classified as a nerve agent. It is colorless, tasteless, and odorless, and is lethal even in very small amounts. Tabun was the first nerve agent to be discovered and was developed in Germany in the 1930s as part of a secret chemical weapons program.

History[edit | edit source]

Tabun was discovered in 1936 by a team of German scientists led by Gerhard Schrader. The team was originally tasked with developing new types of pesticides, but they soon realized that the compound they had created was far too toxic for such use. Instead, it was adopted by the German military and produced in large quantities during World War II, although it was never used in combat.

Properties and Effects[edit | edit source]

Tabun is a liquid at room temperature, but it can easily evaporate and become a gas. It is less volatile than some other nerve agents, which means it is less likely to become airborne and can persist in the environment for longer periods of time.

Exposure to tabun can occur through inhalation, ingestion, or skin contact. The compound works by inhibiting the enzyme acetylcholinesterase, which is necessary for the proper functioning of the nervous system. This leads to a buildup of the neurotransmitter acetylcholine, causing overstimulation of muscles and glands throughout the body.

Symptoms of tabun poisoning can include difficulty breathing, blurred vision, vomiting, and seizures. Without immediate treatment, exposure to tabun can be fatal.

Treatment and Decontamination[edit | edit source]

The effects of tabun can be counteracted with the use of antidotes such as atropine and pralidoxime, which must be administered as soon as possible after exposure. Decontamination can be achieved by removing contaminated clothing and washing the skin with soap and water.

See Also[edit | edit source]





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Contributors: Prab R. Tumpati, MD