Tebuconazole

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Tebuconazole

Tebuconazole is a triazole fungicide used in agriculture to protect crops from a variety of fungal diseases. It is known for its broad-spectrum activity and is commonly applied to crops such as cereals, grapes, peanuts, and rapeseed. Tebuconazole works by inhibiting the biosynthesis of ergosterol, an essential component of fungal cell membranes, thereby preventing the growth and reproduction of the fungi.

Chemical Properties[edit | edit source]

Tebuconazole has the chemical formula C_16H_22ClN_3O and a molecular weight of 307.82 g/mol. It is a systemic fungicide, meaning it is absorbed by the plant and distributed throughout its tissues, providing internal protection against fungal pathogens.

Mode of Action[edit | edit source]

Tebuconazole belongs to the demethylation inhibitor (DMI) class of fungicides. It inhibits the enzyme C14-demethylase, which is involved in the biosynthesis of ergosterol. By disrupting the production of ergosterol, tebuconazole compromises the integrity of the fungal cell membrane, leading to cell death.

Uses[edit | edit source]

Tebuconazole is used to control a wide range of fungal diseases, including:

It is applied as a foliar spray, seed treatment, or soil drench, depending on the crop and the specific disease being targeted.

Environmental Impact[edit | edit source]

Tebuconazole is considered to have moderate persistence in the environment. It can be toxic to aquatic organisms and should be used with caution to avoid contamination of water bodies. Proper application techniques and adherence to recommended usage guidelines are essential to minimize environmental impact.

Safety and Regulation[edit | edit source]

Tebuconazole is classified as a Group 3 fungicide by the Fungicide Resistance Action Committee (FRAC). It is important to follow resistance management strategies, such as rotating with fungicides from different groups, to prevent the development of resistant fungal strains.

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Categories[edit | edit source]



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Contributors: Prab R. Tumpati, MD